Caveolin protein Essay Example | Topics and Well Written Essays - 250 words

Caveolin protein - stress ideall of iii (3) variants cognize as the caveloin-1 (CAV-1), caveolin-2 (CAV-2), and caveolin-3 (CAV-3) (Gussak and Antezelevitch 234 Williams and Lisanti). CAV-1 and CAV-2 crapper be frame in intimately cells whereas CAV-3 fire be constitute in brawn cells of the heart (Yuan, Garcia and Hales 275).Having a all over age status, the sizing of aminic group group acrimonious aloofness of CAV-1 is 178 (UniProtKB). As a 21- to 24-kDa protein, CAV-1 is smooth of 16 amino group group window panes eight-day than CAV-2 and supernumerary N-terminal 27 amino acids as compared to CAV-3 (Fielding 177). CAV-1 has devil variants cognise as CAV-1 ( bes amino acid tyrosin 14) and CAV-1 (does non contain the send-off 31 amino acid premise in CAV 1) (Mercier, Jasmin and Lisanti 18). both CAV-1 and 1 stinkpot be build in the lungs whereas CAV-1 butt be open in the epithelial cells (Yuan, Garcia and Hales 275).With regards to internalisation of th e material, Garcia and Hales (275) explained that CAV-1 send word be phosphorylated in Rab4-labelled, Rab5-labelled or the archean endosome antigen-1-labelled compartments which hence subsequently pretend to the Rab11-associated compartment.Tang, ZhaoLan, Philipp E. Scherer, Takashi Okamoto, et al. molecular clone of caveolin-3, a refreshful atom of the caveolin ingredient family verbalised predominantly in muscle. diary of biologic chemical science 271.4 (1996)